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ACTIVATION OF PIG BRAIN GLUTAMINASE
Author(s) -
Svenneby Gerd
Publication year - 1971
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1971.tb05078.x
Subject(s) - glutaminase , amidohydrolase , chemistry , bromide , phosphate , enzyme , iodide , ammonium chloride , tris , glutamine , ammonium , fluoride , glutamate receptor , biochemistry , carbamoyl phosphate synthetase , medicinal chemistry , nuclear chemistry , inorganic chemistry , organic chemistry , amino acid , receptor
Pig brain glutaminase (EC 3.5.1.2, l ‐glutamine amidohydrolase) is activated by certain anions (e.g. phosphate, fluoride, carboxylic acids) and inhibited by others (e.g. chloride, bromide, iodide and glutamate). The only cation which has been found to activate the enzyme is the ammonium ion. This applies to both the tris‐HCl form and the phosphate‐borate form of glutaminase.