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WALLERIAN DEGENERATION: A SEQUENTIAL PROCESS
Author(s) -
Simon R. G.,
Wade R. R.,
DeLarco J. E.,
Baker MayLouise
Publication year - 1969
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1969.tb09895.x
Subject(s) - wallerian degeneration , degeneration (medical) , myelin , process (computing) , neuroscience , pathological , biology , central nervous system , pathology , medicine , computer science , operating system
Abstract —A study of Wallerian degeneration as a function of time has indicated that the degenerative process is sequential, that it begins with myelin that was laid down last and progresses toward myelin that was laid down first. It is proposed that Wallerian degeneration is a relatively poor model for the study of degeneration of nervous tissue in many pathological conditions.