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SYNTHESIS OF RNA IN NEURONS OF THE HYPOGLOSSAL NERVE NUCLEUS, AFTER SECTION OF THE AXON, IN MICE
Author(s) -
Haddad A.,
Iucif Sálua,
Cruz A. R.
Publication year - 1969
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1969.tb08974.x
Subject(s) - hypoglossal nucleus , hypoglossal nerve , nucleus , rna , axon , cytoplasm , anatomy , uridine , biology , chemistry , microbiology and biotechnology , tongue , biochemistry , pathology , medicine , gene
— Synthesis of RNA in neurons of the hypoglossal nerve nucleus after axonal section was studied by means of [5‐ 3 H]uridine administration and radioautographic counting techniques in mice. The results of the experiments were evaluated by counts of silver grains over the nucleoplasm and cytoplasm of the neurons. RNA synthesis was greater in neurons after axonal section, and this increase was evident from 12 hr after the operation. The greatest increases in the operated side were observed in the 1st, 2nd and 3rd days after operation. In the 7th and 14th days RNA synthesis was still greater in the hypoglossal nucleus of the sectioned nerve but the difference in the control nucleus was not so striking. In the 30th day synthesis of RNA in left and right hypoglossal nuclei was comparable.