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FAST AND SLOW PHASES OF AXOPLASMIC FLOW IN VENTRAL ROOT NERVE FIBRES 1
Author(s) -
Ochs S.,
Johnson J.
Publication year - 1969
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1969.tb08972.x
Subject(s) - axoplasmic transport , anatomy , spinal cord , nerve root , axoplasm , chemistry , biophysics , axon , biology , neuroscience
— The pattern of activity found in ventral roots removed at different times after seventh lumbar and first sacral cord injections of [ 3 H]leucine gave evidence for fast and slow phases of axoplasmic flow. An intra‐axonic location was shown for the fast flow by the block of downflow produced by freezing a narrow region of the ventral root, by reduction of downflow on preinjection of puromycin into the cord and by radioautography of ventral roots. Separate mechanisms appear to be required to account for the fast and slow phases of axoplasmic flow.