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RELEASE OF γ‐AMINOBUTYRIC ACID INTO THE FOURTH VENTRICLE INDUCED BY STIMULATION OF THE CAT'S CEREBELLUM
Author(s) -
Obata K.,
Takeda K.
Publication year - 1969
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1969.tb05948.x
Subject(s) - cerebellum , stimulation , fourth ventricle , aminobutyric acid , neuroscience , chemistry , axon , ventricle , medicine , biology , endocrinology , anatomy , biochemistry , receptor
— The fourth ventricle of the cat was perfused and the release of γ‐aminobutyric acid (GABA) into the perfusate was measured. GABA was released at a rate of 6·69 × 10 −10 moles/min and increased about three times during cerebellar cortical stimulation at 200/sec. It is suggested that GABA is released from axon terminals of Purkinje cells in cerebellar subcortical nuclei.