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PROTEIN SYNTHESIS IN NORMAL AND SCRAPIE MOUSE BRAIN
Author(s) -
Millson G. C.,
Hunter G. D.
Publication year - 1968
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1968.tb08940.x
Subject(s) - in vivo , scrapie , myelin , in vitro , protein biosynthesis , microsome , mitochondrion , biology , biochemistry , amino acid , chemistry , microbiology and biotechnology , medicine , endocrinology , central nervous system , prion protein , genetics , disease
— Damage to the brain as a result of an intracerebral injection of physiological saline does not appreciably affect the rate of protein synthesis in mouse brain. The in vivo and in vitro incorporation of labelled amino acids into mitochondria and their in vivo incorporation into nuclei, microsomes, nerve ending particles, myelin and cell sap were compared in normal and scrapie‐affected mice. No significant differences were found.