Premium
INFLUENCE OF AGE IN THE INCORPORATION OF [14C]GLYCINE INTO ISOLATED RAT NERVE SEGMENTS IN VITRO
Author(s) -
Matheson D. F.
Publication year - 1968
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1968.tb06194.x
Subject(s) - sciatic nerve , in vitro , glycine , rna , linear relationship , endocrinology , biology , medicine , chemistry , anatomy , biochemistry , amino acid , gene , statistics , mathematics
—(1) Sciatic nerves of young rats have been shown to incorporate [ 14 C]glycine in vitro into the protein fraction at a higher rate than nerves from adult rats under the same conditions. (2) Whilst there is little change in the DNA content of the sciatic nerve of rats with age, there is a is noticeable decline in the RNA content with age. (3) There a linear relationship between the specific activity of the protein fraction and the RNA content of the sciatic nerve under in vitro conditions. (4) There is a decline in the specific activity of the protein fraction with age when expressed against DNA. (5) A linear relationship exists between the logarithm of the specific activity and the length of the femur.