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TURNOVER OF RIBOSOMAL RNA IN THE RAT BRAIN *
Author(s) -
Dawson D. M.
Publication year - 1967
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1967.tb09505.x
Subject(s) - ribosomal rna , rna , ribosome , 5s ribosomal rna , centrifugation , 50s , biochemistry , microsome , differential centrifugation , microbiology and biotechnology , biology , chemistry , enzyme , gene
SUMMARY Ribosomal RNA from rat brain has been partially purified by sodium dodecyl‐sulphate treatment of microsomes, and density gradient centrifugation. The apparent half‐life of ribosomal RNA after labelling with a pyrimidine precursor was 6 days. Classes of ribosomal RNA with longer half‐lives could not be excluded. There was evidence for re‐utilization of the labelled precursors.