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Maternal screening and postpartum vaccination for measles infection in Japan: a cohort study
Author(s) -
Shoda A,
Hayashi M,
Takayama N,
Oshima K,
Nishikawa M,
Okazaki T,
Negishi M,
Hayashida S,
Watanabe H,
Inaba N
Publication year - 2011
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2010.02764.x
Subject(s) - medicine , measles , vaccination , pregnancy , obstetrics , measles vaccine , immunology , immunity , measles virus , adverse effect , antibody , pediatrics , immune system , genetics , biology
Please cite this paper as: Shoda A, Hayashi M, Takayama N, Oshima K, Nishikawa M, Okazaki T, Negishi M, Hayashida S, Watanabe H, Inaba N. Maternal screening and postpartum vaccination for measles infection in Japan: a cohort study. BJOG 2011;118:88–92. We investigated the prevalence of measles‐sensitive pregnant women and the clinical usefulness of measles vaccination in postpartum women. Measles antibody levels were measured in 751 pregnant women. Forty‐four women were vaccinated postpartum, and screened for antibody levels and adverse effects 1 month after vaccination. The prevalence of measles‐sensitive pregnant women was 10–20%, with the highest prevalence in those under 24 years of age. Almost all (97.7%) vaccinated women acquired immunity, and did not show any adverse effects. Serum measles antibody levels should be determined in all pregnant women as a screening tool, and sensitive women should be vaccinated immediately after delivery.