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Prevention of mother‐to‐child transmission of HIV in resource‐rich and ‐poor settings
Author(s) -
Mepham SO,
Bland RM,
Newell ML
Publication year - 2011
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2010.02733.x
Subject(s) - breastfeeding , medicine , transmission (telecommunications) , caesarean section , optimism , developing country , human immunodeficiency virus (hiv) , safer , pregnancy , environmental health , pediatrics , family medicine , psychology , economic growth , computer security , biology , computer science , genetics , social psychology , electrical engineering , engineering , economics
Please cite this paper as: Mepham S, Bland R, Newell M‐L. Prevention of mother‐to‐child transmission of HIV in resource‐rich and ‐poor settings. BJOG 2011;118:202–218. Without prevention, a third of HIV‐exposed infants acquire HIV in breastfeeding populations before, during, or after delivery through mother‐to‐child transmission (MTCT). Whereas MTCT is now a sentinel event in resource‐rich countries with antiretroviral prophylaxis, caesarean section, and avoidance of breastfeeding, this is not yet the case in resource‐poor settings because breastfeeding is crucial to infant survival. Recent advances in postpartum maternal and infant prophylaxis enables safer breastfeeding, and increasing numbers of women accessing treatment and prevention of MTCT services in sub‐Saharan Africa is leading to optimism that MTCT could be eliminated here also, as reflected in the UNAIDS target of 2015.