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The use of misoprostol in obstetrics and gynaecology
Author(s) -
Elati A,
Weeks AD
Publication year - 2009
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2009.02329.x
Subject(s) - misoprostol , medicine , obstetrics , gestation , pregnancy , obstetrics and gynaecology , gynecology , abortion , genetics , biology
Misoprostol, although originally introduced as a therapy for gastric ulcers, is now widely used in reproductive health. For some indications it is now the optimal choice, whilst for others it provides an important alternative, especially in low‐resource settings. The optimal dose varies widely from 20 to 600 mcg depending on the indication and gestation. Use of the correct dose is important, too low a dose will be ineffective and overdosage can be dangerous for mother and baby. Evidence‐based information about the safest regimens for multiple pregnancy indications are therefore provided in this review.