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Increased maternal BMI is associated with an increased risk of minor complications during pregnancy with consequent cost implications
Author(s) -
Denison FC,
Norrie G,
Graham B,
Lynch J,
Harper N,
Reynolds RM
Publication year - 2009
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2009.02222.x
Subject(s) - medicine , body mass index , pregnancy , overweight , underweight , population , obstetrics , pediatrics , genetics , environmental health , biology
Objective To investigate the effect of maternal body mass index (BMI) on minor complications, associated additional medication use during pregnancy and the consequent cost implications. Design Retrospective analysis of case notes. Setting Labour wards, tertiary referral hospital, Royal Infirmary Edinburgh, UK. Population Six hundred and fifty‐one women with a singleton pregnancy over four separate time periods in 2007 and 2008. Methods Descriptive statistics, univariate and multivariate logistic regression analysis and cost analysis using standard techniques and inflation indices. Main outcome measures Minor complications, use of medications during pregnancy and consequent incremental costs from the perspective of the National Health Service (NHS). Results 42.4% of women were overweight or obese (BMI ≥ 25 kg/m 2 ). Higher BMI during the first trimester (BMI ≥ 30 kg/m 2 compared with BMI < 25 kg/m 2 ) was associated with an increased risk of minor complications including symphysis pubis dysfunction (OR 3.97; 95% CI 2.19–7.18), heartburn (OR 2.65; 95% CI 1.42–4.94) and chest infection (OR 8.71; 95% 2.20–34.44) and with drugs used to treat these complications including Gaviscon (OR 3.52; 95% CI 1.78–6.96). The mean incremental (additional) NHS costs per woman for treating minor complications increased with maternal BMI were £15.45/woman, £17.64/woman and £48.66/woman for BMI < 25 kg/m 2 , BMI ≥ 25 to <30 kg/m 2 and BMI ≥ 30 kg/m 2 respectively. Conclusions Increased maternal BMI is associated with increased risk of developing minor complications during pregnancy; use of medications associated with treating these conditions and has significant NHS costs.