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An overview of proteomic and metabolomic technologies and their application to pregnancy research
Author(s) -
Horgan RP,
Clancy OH,
Myers JE,
Baker PN
Publication year - 2009
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2008.01997.x
Subject(s) - context (archaeology) , metabolomics , proteomics , relevance (law) , computational biology , data science , omics , bioinformatics , biology , computer science , gene , genetics , political science , paleontology , law
‘Omic’ technologies represent a strategy towards high‐throughput, simultaneous analysis of thousands of biological molecules. Their development has been accelerated in the post‐genomic era since these molecules represent the interaction of genes and environment or the ‘functional genome’. Omic domains are of particular interest in the search for predictive disease biomarkers and have additional relevance in understanding pathophysiology and the development of molecularly targeted therapeutics. This review examines the fields of proteomics and metabolomics in the context of obstetrics and gynaecology, including a discussion of methodology, challenges, potential applications and current research.