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The fetal sex ratio and metabolic, biochemical, haematological and clinical indicators of severity of hyperemesis gravidarum
Author(s) -
Tan PC,
Jacob R,
Quek KF,
Omar SZ
Publication year - 2006
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2006.00947.x
Subject(s) - ketonuria , hyperemesis gravidarum , medicine , fetus , obstetrics , pregnancy , population , gynecology , vomiting , endocrinology , biology , diabetes mellitus , environmental health , genetics
The association between female fetal sex and hyperemesis gravidarum is well established in European and North American populations. The association between female fetuses and severity of hyperemesis remains uncertain. A retrospective study based on case notes review of 166 Asian women hospitalised for hyperemesis was performed. Female fetuses were significantly associated with hyperemesis in our population ( P = 0.004, OR 1.6, 95% CI 1.2–2.2) as well as associated with severe ketonuria and high urea. When both severe ketonuria and high urea were present at initial hospital admission for hyperemesis, 83% (95% CI 66–93) of the fetuses were female.