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Sperm motility in the semen analysis affects the outcome of superovulation intrauterine insemination in the treatment of infertile Asian couples with male factor infertility
Author(s) -
Lee Vincent M.S.,
Wong Joycelyn S.Y.,
Loh Sheila K.E.,
Leong Noel K.Y.
Publication year - 2002
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2002.01034.x
Subject(s) - sperm , infertility , pregnancy rate , pregnancy , sperm washing , gynecology , insemination , male infertility , andrology , semen , artificial insemination , in vitro fertilisation , sperm motility , biology , obstetrics , fertility , population , medicine , genetics , environmental health
Objective To ascertain the relationship between the initial and unprocessed sperm parameters and pregnancy rates in SOIUI, for Asian couples with male factor infertility Design Retrospective study. Setting A large government tertiary‐care women's hospital with 15,000 deliveries per year Population One thousand four hundred and seventy nine couples undergoing 2846 cycles of SOIUI Methods All couples enrolled in the SOIUI programme were analysed, comparing initial sperm parameters and the post‐processed total motile sperm, against pregnancy rates per cycle Main outcome measures Pregnancy rates in relation to initial sperm parameters and post‐processed total motile sperm Results Ninety‐three percent of the couples had male factor infertility. The average normal forms for these men was 14.7%. Overall pregnancy rate was 12.1% per completed SOIUI cycle. We found a significant drop in pregnancy rates if the percentage of motile sperms in the unprocessed sperm sample fell below 30%. We also found that insemination of at least 1 million motile sperm resulted in a significant increase in pregnancy rates Conclusions We recommend SOIUI as an effective treatment of suitable couples with male infertility, before embarking on IVF. However, if the initial percentage of motile sperm fell below 30%, or if after processing, the total motile sperm count was fewer than 1 million, these couples should consider in vitro fertilisation