Premium
The predictive value of serum 1,5‐anhydro‐D‐glucitol in pregnancies at increased risk of gestational diabetes mellitus and gestational impaired glucose tolerance
Author(s) -
Tam WingHung,
Rogers Michael Scott,
Lau TzeKin,
Arumanayagam Mano
Publication year - 2001
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2001.00173.x
Subject(s) - gestational diabetes , medicine , gestation , impaired glucose tolerance , diabetes mellitus , glucose tolerance test , plasma glucose , endocrinology , gestational age , predictive value , obstetrics , risk factor , pregnancy , receiver operating characteristic , type 2 diabetes , insulin resistance , biology , genetics
The objective of the study was to determine the efficacy of 1,5‐anhydro‐D‐glucitol (1,5 AG) for the prediction of gestational diabetes and gestational impaired glucose tolerance (GIGT). One hundred and eighty‐five pregnant women with epidemiological risk factors of gestational diabetes or GIGT underwent 75 g oral glucose tolerance test and plasma 1,5 AG assay at 26 to 28 weeks of gestation. There was no significant difference in plasma 1,5 AG either before or after an oral glucose load. The area under the receiver operator characteristic curve for 1,5 AG was only 0.485 which implies that 1,5 AG is a poor predictor of GIGT or gestational diabetes.