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Medical termination of pregnancy at 63 to 83 days gestation
Author(s) -
Gouk Elaine V.,
Lincoln Karen,
Khair Anu,
Haslock Joanne,
Knight June,
Cruickshank Derek J.
Publication year - 1999
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1999.tb08320.x
Subject(s) - misoprostol , mifepristone , medical abortion , medicine , pregnancy , obstetrics , regimen , gestation , abortion , gynecology , observational study , surgery , genetics , biology
Objective To assess the efficacy of a medical regimen for the termination of pregnancy within the gestational age range of 63 to 83 days. Design Prospective observational study. Setting Gynaecology department within a district general hospital. Population Women attending t0068e pregnancy advisory clinic between June 1996 and December 1997. Methods The medical regimen used was mifepristone 200 mg orally followed after 36 to 48 h by misoprostol 800 μg administered vaginally. Main outcome measures The success rate of the medical termination of pregnancy regimen, where success was defined as achieving complete abortion without the need for secondary intervention by either surgical or repeat medical means. Results Primary medical termination of pregnancy was chosen by 253 (80.8%) of the 313 women and was successful in 239 (94.5%). Repeat medical treatment achieved completion of the abortion in a further three women (1.2%) and surgical evacuation of the uterus was required in 10 (4.0%). One woman declined further intervention after failed medical treatment but subsequently miscarried. Conclusions The combination of mifepristone and misoprostol is effective for the termination of pregnancy for gestations of 63 to 83 days.