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A prospective placebo controlled double blind randomised study to investigate the use of indoramin to prevent post‐operative voiding disorders after surgical treatment for genuine stress incontinence
Author(s) -
Watson A. J. S.,
Currie I.,
Jarvis G. J.
Publication year - 1999
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1999.tb08242.x
Subject(s) - medicine , placebo , placebo group , double blind study , prospective cohort study , anesthesia , double blind , significant difference , surgery , physical therapy , alternative medicine , pathology
A prospective placebo controlled double blind randomised study was undertaken to investigate the use of indoramin an alpha blocker to prevent post‐operative voiding disorders after surgical treatment for genuine stress incontinence. Fifty‐six patients were randomised to receive indoramin 20 mg orally twice a day or identical placebo from the first post‐operative day until discharge from hospital. After seven exclusions, 49 patients were included in the study. There was no significant differcnce between the treatment (indoramin) group and placebo group for any of the outcomes measured. The routine use of indoramin to prevent post‐operative voiding problems cannot be justified on the basis of these data.