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Do routine antibiotics after loop diathermy excision reduce morbidity?
Author(s) -
FodenShroff J.,
Redman C. W. E.,
Tucker H.,
Millinship J.,
Thomas E.,
Warwick A.,
Jones P. W.
Publication year - 1998
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1998.tb10268.x
Subject(s) - medicine , diathermy , placebo , surgery , antibiotics , colposcopy , cervical cancer , alternative medicine , pathology , cancer , microbiology and biotechnology , biology
Objective To evaluate whether routinely giving an antibiotic after loop diathermy excision of the cervical transformation zone reduced post‐operative vaginal loss. Design Prospective, randomised, double‐blind placebo controlled parallel study. Participants Five hundred women undergoing loop diathermy excision in a colposcopy clinic. Intervention Administration of either ofloxacin 400 mg (2 × 200 mg) once daily for 5 days or an identical placebo. Main outcome measure Vaginal loss, assessed using a pictorial chart. Results No significant difference in post‐operative vaginal loss was found. Conclusion Routine antibiotic prophylaxis after loop diathermy excision is not justified.