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Familial puerperal alactogenesis: possibility of a genetically transmitted isolated prolactin deficiency
Author(s) -
Zargar Abdul Hamid,
Masoodi Shariq Rashid,
Laway Bashir Ahmad,
Shah Nissar Ahmad,
Salahudin Mohammed
Publication year - 1997
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1997.tb11548.x
Subject(s) - prolactin , lactation , endocrinology , medicine , hormone , physiology , biology , pregnancy , genetics
Isolated prolactin deficiency is a rare disorder of which only few cases have been reported. In this study we report a woman and her mother who during their eight pregnancies had puerperal alactogenesis. Hormone evaluation revealed isolated prolactin deficiency in both of them. This report demonstrates the dominant role played by prolactin in puerperal lactation. We postulate the possibility of a genetically transmitted isolated prolactin deficiency.