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Sonographic, stereological and Doppler flow velocimetric assessments of placental maturity
Author(s) -
Burton G. J.,
Jauniaux E.
Publication year - 1995
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1995.tb10849.x
Subject(s) - placenta , stereology , biology , maturity (psychological) , vascular resistance , blood flow , circulatory system , pregnancy , andrology , anatomy , fetus , hemodynamics , medicine , endocrinology , developmental psychology , genetics , psychology
Objective To determine whether sonographic assessments of increasing placental maturity are associated with changes in the theoretical diffusing capacity of the organ and with changes in vascular resistance. Design Placental maturity was assessed sonographically in 10 organs: five were classified as completely immature and five as completely mature. Doppler flow velocimetric recordings were obtained shortly before delivery performed by elective caesarean section. Placental biopsies taken immediately after delivery were analysed stereologically. Results No differences were observed in either placental weight or volume, but the morphometric diffusing capacity of the villous membrane was 40 % higher in the mature than in the immature placentas. Doppler indices did not alter with increasing placental maturity. Conclusions Normal term placentas differ significantly in their diffusion characteristics, even when organ weight and volume remain constant. Umbilical vascular resistance may be heavily influenced by the number of parallel circulatory units offered by the placental lobules.