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The thyroid and pregnancy
Author(s) -
Hall R.,
Richards C. J.,
Lazarus J. H.
Publication year - 1993
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1993.tb15299.x
Subject(s) - obstetrics and gynaecology , medicine , library science , family medicine , pregnancy , genetics , biology , computer science
hyroid disease in pregnancy comprises conditions that affect both the mother and the fetus with potential important consequences for child development. 1 To inform the debate concerning the importance of thyroid disorders in pregnancy and the role of screening for thyroid function, it should be noted that the gestational incidence of hyperthyroidism is 0.20.3%, hypothyroidism 2.5% and thyroid antibody (mainly TPOAb) positivity around 10%. 2 Pregnancy has marked effects on thyroid physiology and autoimmune thyroid disease tends to ameliorate through gestation due to general immunosuppression seen in pregnancy. The presence of thyroid antibodies is associated with infertility and miscarriage. 3 The explanation for these findings is