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Second trimester amniocentesis in twin pregnancies: maternal haemoglobin as a dye marker to differentiate diamniotic twins
Author(s) -
BEEKHUIS J. R.,
BRUIJN H. W. A.,
LITH J. M. M.,
MANTINGH A.
Publication year - 1992
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1992.tb14469.x
Subject(s) - amniocentesis , obstetrics , medicine , amniotic fluid , fetus , gestation , twin pregnancy , prenatal diagnosis , second trimester , pregnancy , gynecology , biology , genetics
Objective To review the use of a membrane‐free haemolysate prepared from maternal blood to distinguish the amniotic sacs at amniocentesis in twin gestation. Setting University Hospital, Groningen. Method Haemoglobin solution prepared from maternal blood. Subjects 63 twin pregnancies having amniocentesis. Results The fetal loss before 28 weeks was 4%. There was no perinatal mortality. Dye was detected in the second sac in 9 of 24 women tested before 1985 and none of the 39 women since, no malformations could be ascribed to the use of the haemolysate. Conclusion The use of the membrane‐free haemolysate is safe, but the technique will probably gradually become redundant because of improved ultrasound.