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Normal amniotic pressure throughout gestation
Author(s) -
FISK N. M.,
RONDEROSDUMIT D.,
TANNIRANDORN Y.,
NICOLINI U.,
TALBERT D.,
RODECK C. H.
Publication year - 1992
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1992.tb14385.x
Subject(s) - gestation , amniotic fluid , medicine , gestational age , obstetrics , ultrasound , amniotic fluid index , fetus , pregnancy , gynecology , radiology , biology , genetics
Objective To characterize amniotic pressure (AP) in pregnancies with normal amniotic fluid volume. Design Observational study, mainly cross‐sectional. Setting Fetal medicine unit within a tertiary referral hospital. Subjects Patients undergoing transamniotic invasive procedures in whom amniotic fluid volume was subjectively assessed as normal on ultrasound. Those beyond 16 weeks with a deepest vertical pool on ultrasound <3.0 or >8.0 cm were excluded. Overall 194 pregnancies were studied on 232 occasions between 7 and 38 weeks gestation. Interventions Manometry readings referenced to the top of the maternal abdomen were obtained via a fluid‐filled line from the needle hub and either connected to a pressure transducer ( n = 190 ) or held vertically against a ruler ( n −42 ). Main outcome measures AP in mm Hg, AP corrected for gestational age (z scores), semi‐quantitative ultrasonic indices of amniotic fluid volume, clinical variables. Results AP in singleton pregnancies increased with advancing gestation ( P <0.001 ), and the sigmoid‐shaped regression curve plateaued in the mid‐trimester. AP z scores were not influenced by volume‐related phenomena such as twin gestation, the deepest vertical pool, or amniotic fluid index, nor by maternal age, parity, gravidity, fetal sex, or subsequent spontaneous preterm delivery. Conclusions These findings suggest that AP is not principally determined by intrauterine volume. We speculate that AP, which reflects change in uterine tension as a function of radius, may instead be determined by gestation‐specific anatomical and hormonal influences on gravid uterine musculature. A reference range for AP has been constructed for use in amnioinfusion and amnioreduction procedures.