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Cord insulin and C‐peptide—distribution in an unselected population
Author(s) -
STANLEY K. P.,
FRASER R. B.,
MILNER M.,
BRUCE C.
Publication year - 1992
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1992.tb13793.x
Subject(s) - medicine , cord blood , insulin , cord , population , birth weight , c peptide , umbilical cord , singleton , pediatrics , obstetrics , pregnancy , biology , surgery , immunology , environmental health , genetics
Objective To assess the distribution of cord blood insulin in an unselected population, and examine its relation to birthweight centiles. Setting District General Hospital in Nottinghamshire. Subjects 209 unselected singleton births. Mean Outcome Measure Cord blood insulin; cord blood C‐peptide; birthweight centiles. Results Hyperinsulinaemic babies (> 97th centile for cord insulin) were found at all birthweight centiles. 15% of high birthweight babies were hyperinsulinaemic. For low birthweight babies, the distribution of cord insulin/C‐peptide was skewed indicating a high number of low values. Hypoinsulinaemic babies were present up to the 50th centile for birthweight. Conclusions Abnormalities of fetal insulinisation may be found in babies of all birthweights.