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Immunoscintigraphy of ovarian endometriosis. A preliminary study
Author(s) -
KENNEDY S. H.,
BARLOW D. H.,
SOPER N. D. W.,
MOJIMINIYI O. A.,
SHEPSTONE B. J.
Publication year - 1988
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1988.tb06532.x
Subject(s) - immunoscintigraphy , endometriosis , ovary , medicine , monoclonal antibody , gynecology , pathology , gastroenterology , antibody , immunology , radioimmunotherapy
Summary. CA‐125 is a membrane antigen detected in the serum of some women with gynaecological disease including endometriosis. We attempted to use a radioiodinated anti‐CA‐125 monoclonal antibody, OC‐125, to image ovarian endometriosis using immunoscintigraphy. Two women with significant endometriosis and normal serum CA‐125 levels had positive immunoscintigraphy. In one woman, all areas of endometriosis were imaged; in the other, endometriosis in one affected ovary was seen, but uptake in the other ovary was less than the extent of the disease.