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A double‐blind randomized controlled trial on the use of prophylactic antibiotics in patients undergoing elective caesarean section
Author(s) -
MAHOMED KASSAM
Publication year - 1988
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1988.tb06531.x
Subject(s) - medicine , caesarean section , double blind , randomized controlled trial , placebo , penicillin , elective caesarean section , antibiotics , surgery , anesthesia , elective surgery , pregnancy , genetics , alternative medicine , pathology , microbiology and biotechnology , biology
Summary. In a double‐blind randomized controlled study 232 patients undergoing elective lower segment caesarean section were randomly allocated to receive a pre‐operative prophylactic dose of a combination of crystalline penicillin and chloramphenicol or a placebo. The two groups were comparable in terms of patient characteristics and operation variables. The group receiving antibiotics had significantly fewer febrile and infectious morbid events and thus spent fewer days in hospital than the group receiving the placebo.