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Defective haemochorial placentation as a cause of miscarriage; a preliminary study
Author(s) -
KHONG T. Y.,
LIDDELL H. S.,
ROBERTSON W. B.
Publication year - 1987
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1987.tb03169.x
Subject(s) - placentation , miscarriage , obstetrics , abnormality , chromosomal abnormality , products of conception , fetus , recurrent miscarriage , pregnancy , medicine , gestation , gynecology , placenta , biology , genetics , karyotype , psychiatry , gene , chromosome
Summary The morphology of the placental bed in idiopathic sporadic and recurrent miscarriages was studied and the findings correlated with the fetal chromosomal pattern where possible. Defective development of haemochorial placentation, which was not necessarily linked with fetal chromosomal abnormality, was seen in association with some miscarriages. These preliminary results, not previously demonstrated, strongly support the concept that miscarriages and pregnancies complicated by pre‐eclampsia and/or small‐for‐gestational‐age infants may be a continuum of disorders with a similar pathology in the placental bed.