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Whole blood viscosity during normal pregnancy
Author(s) -
HUISMAN A.,
AARNOUDSE J. G.,
HUISJES H. J.,
FIDLER V.,
ZIJLSTRA W. G.,
HEUVELMANS J. H. A.,
GOSLINGA H.
Publication year - 1987
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1987.tb02313.x
Subject(s) - viscometer , blood viscosity , viscosity , whole blood , hemorheology , shear rate , hematocrit , relative viscosity , reduced viscosity , shear (geology) , red blood cell , materials science , apparent viscosity , chemistry , medicine , composite material
Summary. In a serial study the changes in whole blood viscosity at different shear rates and its major determinants were determined in 24 healthy women with normal pregnancies. Whole blood viscosity and plasma viscosity were measured with a rotational viscometer. Red cell aggregation was measured by syllectometry. During normal pregnancy we found a decrease in whole blood viscosity at all shear rates until 29 weeks gestation, followed by a smaller increase between 30 and 37 weeks, which was most pronounced at higher shear rates, especially in nulliparae. The changes in whole blood viscosity were to a great extent determined by the changes in haematocrit and plasma viscosity. Haematocrit was more important for whole blood viscosity at lower shear rates, while plasma viscosity had more influence on high shear blood viscosity. The continuous increase in red cell aggregation had no demonstrable influence on low shear blood viscosity as measured in vitro in a rotational viscometer.