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Oral contraceptive use modifies the manifestations of pelvic inflammatory disease
Author(s) -
WØLNERHANSSEN PÅL
Publication year - 1986
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1986.tb08036.x
Subject(s) - salpingitis , pelvic inflammatory disease , medicine , chlamydia trachomatis , chlamydia , gynecology , pelvic infection , laparoscopy , disease , obstetrics , family planning , gastroenterology , population , immunology , surgery , research methodology , environmental health
Summary. A case‐control study was performed on 94 women with acute salpingitis and 12 women with salpingitis and perihepatitis; all patients included in the study were infected with Chlamydia trachomatis and all had been subjected to diagnostic laparoscopy. None of the 12 patients with, but 38 (40%) of the 94 patients without, perihepatitis used oral contraceptives (P=0.002). The geometric mean titre of serum IgG antibodies to C. trachomatis was higher among patients with (1:1021) than among patients without (1:69) perihepatitis (P=0001). Oral contraceptive users had lower geometric mean titre of antibodies to the organism (1:25) than non‐users (1:109, P=0.001). The study suggests that oral contraceptive use may modify the clinical manifestations of chlamydial pelvic inflammatory disease.