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Co‐treatment of the male partner in vaginal candidosis: a double‐blind randomized control study
Author(s) -
BISSCHOP M. P. J. M.,
MERKUS J. M. W. M.,
SCHEYGROND H.,
CUTSEM J.
Publication year - 1986
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1986.tb07818.x
Subject(s) - medicine , placebo , incidence (geometry) , double blind , ketoconazole , randomized controlled trial , treatment and control groups , gynecology , dermatology , antifungal , alternative medicine , physics , pathology , optics
Summary. In a double‐blind study, 117 non‐pregnant women with vaginal candidosis were treated for 3 days with 200 mg‐tablets of ket‐oconazole taken once, twice or three times daily. The incidence of predisposing factors or of a recurrence history did not differ between treatment groups. Their male partners were randomly assigned to receive ketoconazole, 200 mg twice daily or placebo for 3 consecutive days. Cure and recurrence rates were not different in the three treatment groups, with or without simultaneous treatment of the male partner. Treatment of the sexual partner in the three dose‐regimengroups proved not to have influenced the therapeutic effect.