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Quantitative structural studies on human placentas associated with pre‐eclampsia, essential hypertension and intrauterine growth retardation
Author(s) -
BOYD PATRICIA A.,
SCOTT ANDREW
Publication year - 1985
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1985.tb01454.x
Subject(s) - eclampsia , obstetrics , medicine , gestation , fetus , preeclampsia , pregnancy , birth weight , placenta , biology , genetics
Summary. Placentas from pregnancies complicated by pre‐eclampsia, essential hypertension, hypertension complicated by pre‐eclampsia and from normotensive pregnancies resulting in the birth of a singleton small‐for‐dates (SFD) infant have been studied by quantitative mor‐phometry. The findings have been compared with those from placentas of uncomplicated pregnancies. The placentas from pregnancies compli‐cated by pre‐eclampsia and those resulting in a SFD baby had a signifi‐cantly lower total volume, volume of parenchyma and villous surface area when compared with normal pregnancies of comparable gestation. They also had an increase in areas of multiple infarction and in the volume proportions occupied by fetal capillaries. The placentas from women with essential hypertension uncomplicated by pre‐eclampsia were as large as those from normal pregnancies and the villous surface areas were as high. Villous surface arca measurements in the different groups were related to gestation and to fetal weight.