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Correlation of the interpretation of fetal heart rate records with cord plasma erythropoietin levels
Author(s) -
WTDNESS JOHN A.,
TERAMO KARI A.,
CLEMONS GISELA K.,
COUSTAN DONALD K.,
CAVALIERI RALPH L.,
OH WILLIAM,
WELCH GREGORY P.,
SCHWARTZ ROBERT
Publication year - 1985
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1985.tb01104.x
Subject(s) - medicine , fetus , cord , erythropoietin , gestational age , cord blood , fetal heart rate , obstetrics , correlation , pregnancy , heart rate , cardiology , blood pressure , surgery , genetics , geometry , mathematics , biology
Summary. On the basis that fetal levels of plasma erythropoietin (Ep) may reflect fetal oxygenation the primary purpose of the present study was to assess the relation between Ep measured in cord plasma at delivery and the intrapartum fetal heart rate (FHR) record. A scoring system for interpreting FHR recordings blindly was prospectively utilized in 41 selected human pregnancies during the 4 h immediately preceding birth. The correlation of the overall mean FHR score for each individual patient with cord plasma Ep was significant such that the highest Ep levels were observed in those infants with the most abnormal FHR scores. Furthermore, when the birthweights of the infants were adjusted for gestational age, sex, and birth order, birthweight centile was negatively correlated with cord plasma Ep. When both FHR score and birthweight were simultaneously correlated with cord plasma Ep using multiple regression, the combined effect of these two factors improved the association of either alone with both contributing approximately equally.