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Pre‐eclampsia in second pregnancy
Author(s) -
CAMPBELL DORIS M.,
MacGILLIVRAY IAN,
CARRHILL ROY
Publication year - 1985
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1985.tb01064.x
Subject(s) - eclampsia , pregnancy , obstetrics , medicine , biology , genetics
Summary. A total population of pregnant women from Aberdeen City District 1967–1978 has been studied. There were 29 851 pregnancies and 6637 women had a first recorded pregnancy between 1967 and 1978 and had two or more pregnancy events. As expected the incidence of pre‐eclampsia in a second pregnancy was less than that in a first pregnancy, but it was dependent on the outcome of the first pregnancy. If the first pregnancy was complicated by proteinuric pre‐eclampsia than the incidence of the condition in the second pregnancy was similar t o that in a first pregnancy, but women who were normotensive in the first pregnancy had a reduced incidence of the condition in the second pregnancy. The incidence of proteinuric pre‐eclampsia after early abortion <13 weeks), either spontaneous or induced was similar to the population incidence in a first pregnancy, but after a late spontaneous abortion the risk of proteinuric pre‐eclampsia was significantly reduced. Change of civil status of the offspring from first to second pregnancy did not affect the incidence of pre‐eclampsia in a second pregnancy. There was an effect of birthweight in that women who had proteinuric pre‐eclampsia in conjunction with a low‐birthweight baby (<2500g) in their first pregnancy had double the incidence of proteinuric pre‐eclampsia in their second pregnancy. Only a pregnancy of 37 weeks or more is likely to offer protection or ‘immunity’ to pre‐eclampsia in a second pregnancy and even then the effect is moderated by the development of pre‐eclampsia in the first pregnancy.