Premium
Screening for liver metastases from ovarian cancer with serum carcinoembryonic antigen and radionuclide hepatic scintiphotography
Author(s) -
SONNENDECKER E. W. W.,
SOUZA J. J. L.,
HERMAN A. A. B.
Publication year - 1984
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1984.tb05905.x
Subject(s) - carcinoembryonic antigen , medicine , ovarian cancer , technetium , colorectal cancer , gastroenterology , pathology , cancer , nuclear medicine
summary The association between pre‐operative serum carcinoembryonic antigen (CEA) and liver scanning employing technetium ( 99m Tc)‐tin colloid was investigated in 30 women subsequently proven to have primary epithelial ovarian carcinoma to determine whether these two investigations improve the detection of hepatic mtastases. The uer limit of normal for CEA (≥ 5 ng/ml) did not represent the optimal levels for use in predicting ovarian carcinoma nor the presence of liver metastases. But with CEA levels> 10 ng/ml sensitivity for liver metastases was 57%. Liver scanning alone demonstrated metastases in five out of seven patients (71%) with parenchymal liver metastases. The combination of CEA and liver scan was positive in six out of these seven patients (86%).