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Intrapartum infusion of aqueous glucose solution, transplacental hyponatraemia and risk of neonatal jaundice
Author(s) -
SINGHI SUNIT,
CHOOKANG E.,
HALL J. ST E.
Publication year - 1984
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1984.tb03680.x
Subject(s) - jaundice , medicine , transplacental , exchange transfusion , cord , bilirubin , pediatrics , pregnancy , obstetrics , endocrinology , gastroenterology , fetus , surgery , placenta , biology , genetics
Summary. Cord serum sodium levels in three groups of 278 singleton infants, born vaginally at term, were correlated with the incidence of jaundice (serum bilirubin ≥85 μmol/1) in the first 3 days of life. Of the 278 infants, 87 were born to mothers who were given infusions of 5% or 10% glucose in water during labour (group I), 90 were born to mothers who received glucose solution as a vehicle for oxytocin (group II), and 101 to mothers who did not receive any intravenous fluid therapy (control group). Jaundice was seen significantly more frequently in groups I (28/87, 32%) and II infants (30/90, 33%) than in the control group (12/101, 12%) (P<0.01), but when analysed in relation to cord serum sodium levels, the prevalence of jaundice in the normonatraemic infants (serum sodium ≥131 mmol/1) was similar in the three groups. On the other hand, in groups I and II jaundice occurred about 3.5 times more frequently in the hyponatraemic infants [group I (17/32, 53%) and II (20/39, 51%)] than in the normonatraemic infants (P<0.01). The difference was not associated with any other perinatal or neonatal characteristic.