Premium
The investigation of proteinuria in pregnancy using iso‐dalt analysis
Author(s) -
CLARK P. M. S.,
EVANS S. E.,
WEAVER J. B.,
FLORA P. S.,
HUGHES S. H.,
WHITEHEAD T. P.
Publication year - 1984
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1984.tb03674.x
Subject(s) - proteinuria , urine , excretion , medicine , pregnancy , albumin , endocrinology , kidney , biology , genetics
Summary. Urinary protein excretion has been investigated using the iso‐dalt technique in pregnant patients with hypertension and proteinuria, without hypertension but with proteinuria and without either hypertension or proteinuria. This high resolution electrophoretic technique has shown a great variation in the pattern of protein excreted by these patients, particularly those with hypertension. These showed an increased number of protein species in the urine, some of unknown identity. Two urines from this group appeared to contain no detectable albumin. Currently this technique is inappropriate for the routine analysis of urine proteins. However, further studies may determine the diagnostic value of these changes in urine excretion and allow the development of more specific assays.