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Smoking habits and maternal serum a‐fetoprotein levels during the second trimester of pregnancy
Author(s) -
THOMSEN STEN G.,
SALLY LENNARTISAGER,
LANGE AKSEL P.,
SAURBREY NINA,
SCHIOLIER VIBEKE
Publication year - 1983
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1983.tb09300.x
Subject(s) - medicine , gestation , pregnancy , obstetrics , second trimester , third trimester , prospective cohort study , significant difference , first trimester , gynecology , physiology , biology , genetics
Summary. In a prospective study the influence of cigarette smoking on maternal serum a‐fetoprotein levels at 16 weeks gestation was examined. Significantly higher levels were found in 120 smokers compared with 138 non‐smokers (median 54.0 and 44.3 μg/1 respectively, P<0.001). No difference in maternal body weight between the two groups could account for the results. The possibility of smoking‐induced increased permeability of the placental barrier is discussed.