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Use of progestogens as an adjuvant to surgery in the treatment of stage I adenocarcinoma of the uterine corpus
Author(s) -
MOAZZAMI B.,
WALT J. D.,
BOYD N. R. H.
Publication year - 1983
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1983.tb08905.x
Subject(s) - stage (stratigraphy) , medicine , adjuvant , gynecology , oncology , biology , paleontology
Summary. Fifty‐nine patients with proven stage I adenocarcinoma of the uterine corpus were treated by total abdominal hysterectomy and bilateral salpingo‐oophorectomy, followed by gestronal hexanoate intramuscularly for 3 months and then medroxyprogesterone acetate orally for a prolonged period. In the 7‐year period of study, there were no vaginal recurrences, but one patient suffered a recurrence in the inguinal lymph nodes and pelvis. Undesirable side effects did not occur. These results compare favourably with other reported studies in which surgery and radiotherapy were used.