Premium
Value of Schwangerschaftsprotein 1 (SP 1 ) and pregnancy‐associated plasma protein‐A (PAPP‐A) in the clinical management of threatened abortion
Author(s) -
MASSON GORDON M.,
ANTHONY FREDERICK,
WILSON MARY S.
Publication year - 1983
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1983.tb08899.x
Subject(s) - pregnancy associated plasma protein a , pregnancy , abortion , obstetrics , medicine , threatened abortion , vaginal bleeding , gynecology , andrology , biology , fetus , first trimester , genetics
Summary. Pregnancy‐associated plasma protein‐A (PAPP‐A) and Schwangerschaftsprotein 1 (SP 1 ) levels were measured in single serum samples from 60 patients admitted with vaginal bleeding in the first 14 weeks of pregnancy. When based on ultrasound diagnoses the prediction of non‐viability (the predictive value) was 97% for SP 1 and 84% for PAPP‐A. Whereas the prediction of viability (above –2SD of the normal range) with SP 1 was 88% the value with PAPP‐A was only 57%; the poorer result obtained with PAPP‐A probably reflects its longer half‐life. Pregnancy outcome is not related to the duration of bleeding.