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Excretion of oxprenolol and timolol in breast milk
Author(s) -
FIDLER JACK,
SMITH VALERIE,
SWIET MICHAEL
Publication year - 1983
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1983.tb06771.x
Subject(s) - oxprenolol , timolol , breast milk , excretion , chemistry , endocrinology , plasma concentration , medicine , blood pressure , surgery , biochemistry , intraocular pressure
Summary. The excretion of oxprenolol and timolol in breast milk was examined by comparing their concentrations in milk with those in plasma. The mean milk to plasma ratio of oxprenolol was 0.29 (SD 0.14; that for timolol was 0.80 (SD 0.21). The total quantity of either drug ingested by a fully breast‐fed infant is unlikely to be therapeutically significant.