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THE MANAGEMENT OF CHORIOCARCINOMA CAUSING SEVERE THYROTOXICOSIS
Author(s) -
Soutter W. P.,
Norman R.,
GreenThompson R. W.
Publication year - 1981
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1981.tb02233.x
Subject(s) - propylthiouracil , medicine , propranolol , chemotherapy , choriocarcinoma , thyroid , intensive care medicine , pediatrics , surgery
Summary Two patients with metastatic choriocarcinoma complicated by severe thyrotoxicosis, leading to cardiac failure in one instance and thyroid crisis in the other, are described. The successful treatment of these complications is detailed, and routine prophylaxis for high risk patients, using propylthiouracil, oral iodide, propranolol and urgent, aggressive chemotherapy, is recommended.