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A DOUBLE BLIND TRIAL OF EXTRA‐AMNIOTIC OESTRIOL AND PROSTAGLANDIN F 2α GELS IN CERVICAL RIPENING
Author(s) -
Quinn M. A.,
Jmurphy A.,
Kuhn R. J. P.,
Robinson H. P.,
Brown J. B.
Publication year - 1981
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1981.tb01223.x
Subject(s) - prostaglandin f2alpha , prostaglandin , medicine , bishop score , ripening , amniotic fluid , obstetrics , chemistry , pregnancy , cervix , biology , fetus , food science , cancer , genetics
Summary Forty nulliparous patients with a Bishop score of 3 or less were given 15 mg oestriol gel, 10 mg PGF 2α gel or gel alone via the extra‐amniotic route. Both the oestriol and prostaglandin treated patients had a significant increase in Bishop score and a significant reduction in induction‐delivery interval compared to con‐trols. Oestriol gel had significantly less stimulatory effect on uterine activity than prostaglandin gel, indicating a possible local action.