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A COMPARISON OF PLASMA PROSTAGLANDIN LEVELS IN TERM AND PRETERM LABOUR
Author(s) -
Sellers Susan M.,
Mitchell M. D.,
Bibby J. G.,
Anderson Anne B. M.,
Turnbull A. C.
Publication year - 1981
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1981.tb00997.x
Subject(s) - preterm labour , preterm labor , gestation , prostaglandin , prostaglandin f , cervical dilatation , medicine , plasma levels , endocrinology , pregnancy , term (time) , obstetrics , biology , cervix , genetics , physics , cancer , quantum mechanics
Summary Peripheral plasma levels of 13,14‐dihydro‐15‐keto‐prostaglandin F (PGFM) were determined in women during pregnancy and in term and preterm labour. The PGFM concentrations at term were not significantly different from the levels between 26 and 34 weeks gestation. In both term and preterm labour there was a rise in PGFM levels with increasing cervical dilatation although the mean values tended to be lower during preterm labour. These findings may provide an explanation for the effectiveness of prostaglandin synthetase inhibitors in suppressing myometrial activity in preterm labour.