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A CASE OF CLEAR CELL ADENOCARCINOMA OF THE VAGINA IN PREGNANCY
Author(s) -
Davis J. A.,
Wadehra V.,
McIntosh A. S.,
Monaghan J. M.
Publication year - 1981
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1981.tb00989.x
Subject(s) - vagina , adenocarcinoma , metaplasia , pregnancy , in utero , clear cell adenocarcinoma , diethylstilbestrol , squamous metaplasia , medicine , pathology , gynecology , fetus , epithelium , biology , cancer , anatomy , estrogen , genetics
Summary The case is described of a 20 year old pregnant woman with clear cell adenocarcinoma of the vagina who had been exposed to diethyl stilboestrol in utero . This is the second of three cases known to have occurred in Britain. The importance of radical treatment is discussed. Neither cervical nor vaginal intra‐epithelial neoplasia were seen histologically, although squamous metaplasia was widespread, and in some areas was immature and showed atypical features which could be misinterpreted as intra‐epithelial neoplasia. An area of atypical adenosis was noticed, a hitherto rarely observed feature.