Premium
CLOTTING AND FIBRINOLYTIC ACTIVITIES IN PERITONEAL FLUID
Author(s) -
Pattinson H. A.,
Koninckx P. R.,
Brosens I. A.,
Vermylen J.
Publication year - 1981
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1981.tb00962.x
Subject(s) - peritoneal fluid , plasmin , fibrin , peritoneal cavity , coagulation , plasminogen activator , clotting factor , thrombin , fibrinolysis , medicine , endocrinology , chemistry , immunology , biochemistry , surgery , platelet , enzyme
Summary Peritoneal fluid does not clot spontaneously on collection, due to a lack of prothrombin activation, consequent upon a virtual absence of factors V and VIII. Factor VIII related antigen is present in peritoneal fluid in only very small amounts, suggesting that this factor is excluded from the peritoneal cavity, probably by virtue of its size. Slight thrombin activity is demonstrated by the presence of fibrin monomers in the fluid. That peritoneal fluid also contains fibrinolytic activity is shown by high levels of plasminogen and plasmin‐antiplasmin complexes, though no plasminogen activator could be detected. No differences were found in clotting and fibrinolytic activities between fluid taken from these patients with, and those without, laparoscopic evidence of pelvic endometriosis.