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CONSERVATIVE MANAGEMENT OF PITUITARY PROLACTINOMAS; EVIDENCE FOR BROMOCRIPTINE‐INDUCED REGRESSION
Author(s) -
Hancock K. W.,
Scott J. S.,
Lamb J. T.,
Gibson R. Myles,
Chapman C.
Publication year - 1980
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1980.tb04590.x
Subject(s) - bromocriptine , radiological weapon , hyperprolactinaemia , medicine , lesion , surgery , hormone , prolactin
Summary Thirty‐six women with sustained hyperprolactinaemia, 29 showing radiological abnormality of the pituitary fossa, were managed conservatively; 28 accepted bromocriptine treatment which controlled hyperprolactinaemia in all and was associated with improvement in the radiological appearance of the pituitary in 4 cases. Two of the 8 patients who did not accept bromocriptine showed radiological extension of the pituitary lesion; one showed radiological improvement. Bromocriptine should be regarded as a drug to control the pituitary tumour, not merely one which inhibits the endocrine effects.