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INTRAUTERINE DIGOXIN TREATMENT OF FETAL PAROXYSMAL TACHYCARDIA CASE REPORT
Author(s) -
Llngman G.,
Ohrlander S.,
Ohlin P.
Publication year - 1980
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1980.tb04552.x
Subject(s) - digoxin , paroxysmal tachycardia , medicine , paroxysmal supraventricular tachycardia , cardiology , tachycardia , fetus , pregnancy , heart failure , biology , genetics
Summary A patient with fetal paroxysmal supraventricular tachycardia (PST) with a heart rate above 300 beats/minute in the 29th week of pregnancy is described. The fetus showed signs of severe cardiac failure and was, therefore, digitalized by giving the mother 0.5 mg digoxin intravenously on the first day and then 0.25 mg oral digoxin daily throughout the pregnancy. After one day a normal rhythm was observed. The patient was delivered of a healthy girl after 38 weeks of pregnancy. Digoxin concentrations in samples of umbilical cord vein and artery, intrapartum scalp capillary, and amniotic fluid were almost equal, but somewhat lower than in simultaneously obtained maternal serum. Intrauterine digoxin treatment of fetuses with PST is discussed.