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CIRCULATING LEVELS OF PLACENTAL PROTEIN 5 IN THE MOTHER: RELATION TO BIRTH WEIGHT
Author(s) -
Obiekwe B. C,
Grudzinskas J. G,
Chard T.
Publication year - 1980
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1980.tb04544.x
Subject(s) - radioimmunoassay , growth retardation , gestation , predictive value , birth weight , pregnancy , obstetrics , medicine , population , fetus , endocrinology , biology , environmental health , genetics
Summary A total of 914 blood samples was obtained from an unselected population of 400 women between 36 and 40 weeks gestation. Serum PP5 levels were measured by a sensitive radioimmunoassay. After ranking of PP5 levels and birth weight the value of serum PP5 in the diagnosis of intrauterine growth retardation was examined. The sensitivity, predictive value, and specificity of the test were 17.07, 16.66, and 90.25 per cent respectively; these results suggest that serum PP5 levels are less accurate than other biochemical parameters in the identification of fetal growth retardation in late pregnancy.