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PROPRANOLOL AND HYDRALLAZINE IN THE MANAGEMENT OF ESSENTIAL HYPERTENSION IN PREGNANCY
Author(s) -
BottKanner G.,
Schweitzer A.,
Reisner S. H,
JoelCohen S. J,
Rosenfeld J. B
Publication year - 1980
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1980.tb04502.x
Subject(s) - propranolol , medicine , pregnancy , essential hypertension , cardiology , blood pressure , biology , genetics
Summary A combination of propranolol and hydrallazine was administered to 13 patients with longstanding hypertension during 15 pregnancies. Hydrallazine was continued through labour and delivery in all patients, while in eight patients propranolol was discontinued 2 to 15 days before delivery. Blood pressure control was uniformly good and superimposed pre‐eclampsia did not occur during combined therapy. There were 14 livebirths and one unexplained stillbirth. Except for two cases of mild hypoglycemia, there were no neonatal complications.